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(ML) techniques such as genetic algorithms, 31, 32 artificial neural network, 33, 34 Gaussian process regression In recent years, artificial intelligence (AI) and machine learning Level, and many structures need to be optimized at a higher level. Of configurational space has to be sampled at a lower accuracy method To avoid missing the true low-energy conformers, a large portion Methods at different levels predict different To refine the conformer structures and energies (such as force fields Promising candidate structuresĪre then funneled through more costly methods with higher accuracy Fast computational methods with lower accuracy are employed To balance efficiency and accuracy, hierarchical methods have beenĭeveloped. Provide energies for all configurations produced in the search. More often than not, quantum chemistry methods are too expensive to However, they are computationally costly. Higher accuracy in the estimation of molecular energies than forceįields because they describe the interactions and polarization in Quantum chemistry methods such as the density functional theory (DFT)Īnd coupled cluster (CC) theory. Two classes of totalĮnergy approaches are commonly used: force field-based methods and Systematic or stochastic algorithms mentioned before.Ĭhallenge in conformer searches is the sufficientlyĪccurate mapping of energies and structures. Knowledge-based methods usually need to be combined with the different Structure Database (CSD) 26 or the Proteinĭata Bank (PDB). The library is typicallyīased on experimental structures in databases such as the Cambridge Theyįor torsion angles and ring conformations. Sampling is required, and the results may be affected by the randomĭeveloped 24, 25 to achieve more consistent results. 11, 23 Stochastic methods can be applied to larger molecules with high-dimensionalĬonformer spaces, but the predicted conformers may vary. Restricted to predefined, most relevant ranges) based on differentĪlgorithms such as Monte Carlo annealing, 17, 18 minima hopping, 19 basin hopping, 20, 21 distance geometry, 22 and genetic algorithms. Methods randomly sample the phase space of torsion angles (sometimes Numbers of relevant torsion angles, i.e., search dimensions. Limited to small molecules because it scales poorly with increasing 11− 16 These methods can be broadly classified to be either systematicĪ systematic method relies on a grid to sample 1 A variety of methods and tools have been developed to generate diverseĬonformer structures. While keeping bond length and angles fixed. Most search methods focus on sampling the torsion angles in molecules Since theīond lengths and angles are relatively rigid in molecules and theĭifferent conformers originate from the flexible rotational groups, Is commonly applied to make the problem more tractable. 9, 10 For this reason, dimensionality reduction The conformational space (bond lengths,īond angles, and torsions) for even relatively small molecules isĮnormous. One of the persistent challenges in molecular modeling. Of local minima in typical energy landscapes make conformer searches Large size of configurational phase space and the considerable number 8 While one configuration of a small molecule canīe simulated routinely by ab initio methods, the Topic of great interest in computational chemistry, 4 cheminformatics, 5, 6 computational drug design, 7 and structure-based virtual screening. 1− 3 Therefore, identifying the low-energyĬonformers and determining their energy ranking continues to be a To a minimum on the molecule’s potential energy surface (PES).Īny molecule with rotatable bonds has several stable conformer structures,Įach associated with different chemical and electronic properties.Īt ambient temperatures, all the properties of that molecule are theĬombination of the properties of its conformers accessible at the Molecular conformer is a distinct conformation corresponding According to Tinsley, he had recently returned from Europe “in which the singer temporarily escaped demons that had nearly devoured him, he was riding high off the success of the smash album Midnight Love, which was, in turn, fueled by the Goliathan influence of its landmark single ‘Sexual Healing.’” “Being the head coach of the Lakers, and coaching the All-Star Game at the Great Western Forum that day … it just made it a special, almost spiritual-type moment for me.” - Pat Rileyįor Gaye, his appearance at the All-Star Game marked a comeback moment. “Even then the synergy of basketball icons and a musical icon made all the sense in the world.” J” Erving, Earvin “Magic” Johnson, Kareem Abdul-Jabbar, Maurice Cheeks, Larry Bird, Isiah Thomas, Reggie Theus, Moses Malone, Pat Riley, Bill Laimbeer, Andrew Toney, Alex English, Robert Parish, Jamaal Wilkes and more were lined up on opposite free throw lines, facing each other across the court. Now, thirty-five years later, Gaye’s rendition is still the standard by which all other versions are judged ( ).Īs Justin Tinsley wrote in a piece at titled “The players’ anthem when Marvin Gaye sang ‘The Star-Spangled Banner’ at the 1983 All-Star Game” ( )the stars were out, being “a stone’s throw from Hollywood.” The players, including Julius “Dr. Coming off some difficult personal years, Gaye reached deep into his soul, and stirred the crowd as perhaps no other anthem singer had ever done. Dressed impeccably in a blue suit, white shirt and tie, and white pocket square, and wearing sunglasses, Gaye was there to sing the National Anthem at the NBA’s 33rd All-Star game. If you’re a basketball fan, a social activist, a music nerd – and you were alive at the time - you probably remember what you were doing on the afternoon of February 13, 1983, when all eyes were focused on Marvin Gaye as he strolled onto the basketball court at The Forum in Inglewood, California. No one put their own stamp on the anthem and moved the crowd like Marvin Gaye did forty years ago. Over the years there have been some great entertainers performing the national anthem at NBA All Star Games, including Macy Gray, Chaka Khan, and Gladys Knight. This year, Jay Park will be singing the national anthem. On Sunday, February 19, the Utah Jazz will host the NBA All Star Game at Salt Lake City’s Vivint Arena. He talked about issues that resonated in the black community in a very meaningful way.” He was an important guy, artistically, at that time. Kaepernick’s attorney recently said the performers at Super Bowl LIII are “crossing an intellectual picket line” and “saying to themselves, ‘I care more about my career than whether what I’m doing is right.“Marvin Gaye was absolutely on the forefront of. Kaepernick, 31, filed an official grievance against the NFL in October 2017, alleging that teams had colluded to keep him off the field after he kneeled during the national anthem in 2016 to protest police brutality and racial inequality. Knight’s decision to perform at the big game came with controversy related to former San Francisco 49ers quarterback Colin Kaepernick, however. This is who we are, this is how we are and this is what we do. That’s what I feel when I sing this song. “We’ve been singing it forever, but this time I would hope that will feel it so deeply that it will lift them to a higher place. “I hope that this anthem will touch people in a different way,” she said. The Empress of Soul also reflected on the honor in an NFL video released at the time. From curated cocktails and menu items to simply watching with their family and Though it’s always fun seeing famous faces in the crowd at football’s biggest game of the year, it’s also just as exciting to see how they celebrate the Super Bowl just like Us - lounging on their couches with bowls of snacks. This palette contains shades like the soft buttercup and peony, in contrast to the bolder mulberry and rosewood. The bodice of the dress featured has off the shoulder straps and is V neck with a floor-length flowy, A-line skirt. The neutral shades include earthy tones like fawn, charcoal, ivory, and champagne with a hint of metallic in the silver. TheaĪnother extremely contemporary palette, Thea has colors like French lilac, peach, mulberry, eggplant, and primrose to complement shades like marine, navy, sky blue and slate blue. The dress has a flared skirt with an elegant floral embroidered lace over the bust and the spaghetti straps create a keyhole illusion down the back. CameronĬameron includes shades of sapphire, eggplant, violet, primrose, Bordeaux, and claret with the basic shades of ivory, black, dove and fawn that make a compact palette of fall wedding colors. The Athena dress is a flowing A-line gown with one shoulder, ruched bodice and it is made of flat chiffon fabric. The palette has shades like teal, slate blue, cornflower, along with some jewel tones of claret, sapphire and emerald, pastels like mint, blush, cantaloupe, and finally the neutrals that include black, white, ivory, champagne, and charcoal. AthenaĪthena combines some beautiful jewel, yet floral tones with the earthy shades and some brighter fall colors. The chiffon dress that is shown along with this palette is bohemian with off shoulder, with double layer ruffle top adding a fun element. The neutrals include dove, sage, ivory, latte, and black which create the base to incorporate shades like rosewood, claret, mulberry, sapphire, and marine and even some metallic shades of emerald and silver. AllisonĪllison is a palette which while having some muted, shadowy neutrals also has some flamboyant shades of bolder colors. The dress featured is chiffon, floor-length, A-line gown with a plunging V neck and a ruched bodice. These shades can be used to create a rich look that is contrasted by neutrals and pastels. From navy, sapphire, slate, mint to the soft peach, and the bright berry, the colors also include neutral tones like ivory, dove, champagne, and charcoal. This palette features some of the cooler shades and mostly bluish and pinkish tones. You can also check out some of the bridal outfits designed by Kennedy Blue that are very beautiful and elegant. The palettes that are shown below have been created to provide a perfect combination of fall wedding colors and each of them features a bridesmaid’s dress by Kennedy Blue. Theme colors for a wedding are reflected in not only the décor of the venue but also in the bridesmaids’ dresses that complement the overall palette, bringing forth the vibrancy of all the colors that have been used. Given below are some great palettes that have been put together to inspire a very creative look and create a very fitting mood. All the palettes include a touch of some metallic hues and some neutral tones. Fall wedding colors are not restricted to a one-dimensional palette, but will rather allow you to explore a range of shades, starting from oranges and reds, to blue, and violet. We Love Fall Wedding Colorsįall is a season with clear blue skies, burnt orange and gold leaves, crackling yellow fires on hearths and all these warm and vibrant shades can be incorporated in a full palette. This article will discuss some amazing palettes that can be used in a lovely and stunning fall wedding. The warmth of hues in this season give a palette of fall wedding that lifts the spirit of the celebrations, making fall one of the favorite times in the year to hold a wedding. However, fall is one season that allows you to have a combination of different shades. While each season adds a different charm to a wedding and elevates the aesthetics with a beautiful palette of colors, fall remains one of the brightest and most beautiful seasons to hold a wedding in.Įvery other season has almost a set palette for example, summer has a range of soft pastels and winter calls for rich darker colors. ET (though HBO is known to skip weeks for holidays). While HBO has not released a schedule, it's likely they will debut on subsequent Sunday nights at 9 p.m. There will be eight episodes of Euphoria season 2 (just like season 1). His childhood friend Hokari Kanae, classmate Andou Miyako, underclassmate Makiba Rika, English teacher Aoi Natsuki, same year Byakuya Rinne. The protagonist Takatou Keisuke and 6 others are locked up in these hidden white rooms. Description: They wake up in a white room remembering nothing. Characters include our protanist, Takato Keisuke, his childhood friend Hokari Kanae, classmate Ando Miyako, underclassmate Mikaba Rika, English teacher. Duration: 29:43 Views: 120K Submitted: 2 years ago. 17) at 10.05 p.m - so a day after it arrives in the U.S. Six people find themselves trapped in a mysterious futuristic complex, forced to dance to the tune of a sadistic computer game, where failure to follow the game rules results in death. How to watch Euphoria season 2 online in the UKįor our friends across the pond, Euphoria season 2 episode 2 will be debuting on Sky Atlantic today (Monday, Jan. If you're an American traveling abroad and want to use your HBO Max subscription, you'll need to look into the best VPN services. After that, the Movies + HBO package costs $19.98 CAD per month. The VOD Crave platform will receive new episodes of Euphoria season 2 on the same date and time as episodes debut in the U.S.Ĭrave has a 7-day free trial. How to watch Euphoria season 2 episode 2 online in Canadaįortunately, our friends in Canada have a good situation with Euphoria season 2 episode 2 (better than those in the U.K., at least). Oh, and Netflix just canceled two TV shows, so don't expect them to be changing their habits in the new year. His childhood friend Hokari Kanae, classmate Ando Miyako, underclassmate Mikaba Rika, English teacher Aoi Natsuki, same year Byakuya Rinne, and classmate Manaka Nemu. As for something completely different? Well, the third show we're recommending is the utterly bonkers Peacemaker episode 4 that is arriving this week as well. They wake up in a white room remembering nothing The protagonist Takato Keisuke and 6 others are locked up in these hidden white rooms. Looking for more things to watch? This week has new episodes of three of the biggest shows on TV, and we've got the details on This Is Us season 6 episode 3 and The Book of Boba Fett episode 4. The guys watched the below copy of the movie on youtube, as it’s not very readily available on DVD, and you can sync up the commentary and join the guys on this adventure into all things Chuck Norris. The guys try to figure out what level of mental illness Barry has, if Chuck Norris exists at all in the movie, why Danica McKellar is turned on by violence, why the big tournament at the end comes down to brick breaking and much more. Sidekicks is a 1993 American adventure action comedy-drama film directed by Aaron Norris and starring Jonathan Brandis and Chuck Norris. Also, Joe Piscopo is the leader of a Cobra Kaiesque dojo who hates Chuck Norris. is troubled by menacing classmates, so much so that he retreats into a fantasy world where he takes on the role of sidekick to movie idol Chuck Norris. It was the brainchild of James McIngvale -aka 'Mattress Mac'-a well-known furniture outlet owner. Chuck Norris son Eric Norris plays one of the bikers in the restaurant scene, listed as Biker 5 in the credits. In order to help him overcome both his obsession with Chuck and his asthma, his dad (Beau Bridges) decides to have him train in martial arts with the uncle (Mako) of Barry’s teacher (Julia Nickson-Soul), who runs a Chinese food restaurant. Chuck Norris did this film as a favor to his brother Aaron Norris, who was the director. Chuck stars as himself in the various daydreams of superfan Barry (Jonathan Brandis), who imagines himself as Chuck’s sidekick in various scenarios based around Missing in Action, possibly Hard Target (even though it’s a Van Damme movie), westerns, ninjas and more. To escape his real life problems, Barry imagines himself the sidekick of his action hero, Chuck Norris in a series of high-octane adventures taken right out. For this Everything Action commentary, Zach, Chris, Chris Ali and Asa dive into what could possibly be the ultimate Chuck Norris movie, Sidekicks. Everyone doesn’t know their way around the command-line utility. It doesn’t support all metadata types, and some metadata types are difficult to deploy.The Ant Migration tool isn’t the best option for every circumstance, or for every team. The Ant Migration Tool can be integrated with source control tools, so developers can reduce risk and communication breakdowns.It’s possible to automate and control the exact timing of rollouts.Developers can have full control and visibility into the changes that are being deployed.Other benefits of the Ant Migration Tool include: With the Ant Migration Tool you can use continuous integration to compare work and spot incompatibilities throughout the development process. The Ant Migration Tool allows you to keep the two environments in sync. In the event that two people are working on separate projects in different environments, it can be hard to know whether their changes will be compatible with one another. One of the main benefits of the Ant Migration Tool is the ability to synchronize different Salesforce orgs.
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Use fast, hardware-accelerated video exporting with NVIDIA® CUDA™, AMD APP, or Intel® Quick Sync Video technologies. Export screen and gameplay recordings to popular formats and devices! Select one of many predefined profiles and push a button to export your recordings to popular formats, devices, Facebook, or YouTube™. All your Windows desktop actions and gameplay will be recorded in a single video file. Stream gameplay and desktop activity to popular services! Action! LIVE Streaming service allows streaming all your gameplays, videos, or desktop activity to popular streaming services like, YouTube, hitbox, Ustream, Livestream, Aliez and more! Continuous Windows desktop and gameplay recording! With Action! in active screen recording mode, you can record your videos continuously, no matter how many times you switch from Windows desktop to fullscreen gameplay and back. Instant access to your PC games, documents, and applications in an outstanding HD quality. Play PC games on Android! Discover the best remote control software for your PC! Play your favorite PC games and control your Windows desktop with Android devices or another PC. Record smooth high framerate HD videos of your desktop and applications activity, add microphone audio commentary, and create great tutorials with ease! Remotely access your PC with Android devices or another PC. Smooth Windows HD desktop recording, easy tutorial creation! The software defines a new standard of performance and user experience for real-time desktop recording software. Action! outstanding performance and GPU utilization allow the smoothest real-time HD gameplay video recording ever! Display current and average game framerate (FPS) during gameplay and save your benchmark results. The screen recorder defines a new standard of user experience for games benchmarking, gameplay, and Windows desktop real-time recording software. Built-in screen and gameplay recording manager allows to browse, delete selected items, and export recordings to popular formats and devices. Mirillis Action! is compact, stylish, and user-friendly. and more! Download Mirillis Action! Offline Installer Setup for Windows. With the software, you can record and stream your gameplay, web player videos, record music, capture screenshots, remotely access your PC, play PC games with Android devices. i'll report back with the conclusion / resolve.Mirillis Action! allows streaming and real-time recording of Windows desktop in a superb HD video quality. I'm currently in the process of emailing their support team. it seems like anything MP4 whether its normal mp4, mp4 AMD, mp4 Intel quicksync, it just crashes either my game or app. but when i use MP4 AMD APP i get signifigant performance drops. i prefer using Intel QuickSync over the MP4 AMD APP because the performance drop is virtually nothing. the only format that doesn't crash my game or program is AVI. (And to import to vegas MP4 AMD APP, in vegas folder FileIO Plug-Ins, delete compoundplug.dll like this, you can import dual audio and videos decently). Do not forget, in video configuration (windows), turn to High performance, not balanced or eco. My R9 380 works fine that way.Īction works better that way, but it depends. And at last, but not least, in video configuration (action), change Bitrate to normal, 0-255, 80% or 100%, at same configuration in export config, turn on the AMD APP. Postat inițial de SerginhoHDg:Yeah, AVI take much space in hdd, it works fine in AMD video card, MP4 (with amd plugin), update a quick time in apple site, (if you are using windows 10, try update all thats stuffs). Games in particular that are having issues (Full Screen or Windowed Borderless), Diablo 3, Rise of the Tomb Raider, Rust, GTA5, WoW, ETC. Specs - Western Digital caviar black 500gb (Main OS) 1tb WD Black (Storage), Intel i7 4790k 4.4ghz (Stock clocks, Chipset and Video Driver upto date), MSI Gaming 5 z97, MSI R9 390 8gb (Stock Clocks, Drivers up to date), 16gb DDR3 1600mhz, Windows 10 64bit pro (Fully updated), OCZ ZT-Series 750W Power Supply, 32inch Samsung display 1080p 60hz. I am running out of ideas here and its really frustrating. I've tried switching it from recording per application (DX12, ect) to just record active screen. Tried in compatibility mode for windows 8 - no dice! it doesn't work whether its on my main drive or my main storage drive. Switching Hard drives for the output file. Here is some other things i've tried to fix. AVI and MP4, i've also tried messing with the bitrate and quality. I am using the Intel Quicksync format but i also tried. or it could be a few minutes in of the actual recording. it could be when i hit the record button. My problem is that it causes my games to crash or the recorder to crash. Just bought Mirillis Action! (Using whatever is the newest version is today). Avulsion injuries do not involve the syndesmosis and the ankle remains stable. This results in either a pure ligamentous injury (complete or partial tear) or avulsion of the tip of the fibula (the lateral malleolus). A pure inversion injury will result in tension being applied to the supporting soft tissues of the lateral ankle, particularly the lateral collateral ligament. Most ankle injuries occur because of an inversion injury. Pathology EtiologyĪnkle fractures may be the result of a vast array of injuries that range from an inversion injury to a complex high energy trauma sporting injury. inability to bear weight both immediately after injury and during clinical examinationĪn ankle x-ray series (AP and lateral views) is usually all that is needed to make a diagnosis.point tenderness at the posterior edge or tip of the medial malleoulus.point tenderness at the posterior edge or tip of the lateral malleoulus.The Ottawa ankle rules allow evidence-based decision making regarding the need for plain radiographs in patients with a traumatic ankle injury.Ī plain film radiograph is indicated in the setting of trauma if there are any of the following clinical examination findings 1: Most patients present following an episode of trauma with ankle pain, tenderness and an inability to weight bear. Risk factorsĬigarette smoking and obesity are both risk factors for ankle fractures. motor vehicle accident, sporting injury), while older patients present following minor trauma (e.g. Young patients present following injuries in relatively high-energy trauma (e.g. Ankle injuries, like many fractures have a bimodal distribution. |
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